Founded in 2018, Giam Pharma was established to develop intelligent oncology therapies.
Fraisinib: Innovation Against Tumors Resistant to Conventional Therapies
The first molecule to inhibit GARS1 for targeted and tolerable treatments.


Key Highlights
Core Strengths
Preclinical Trials
International Patent Protection
Very Low Systemic Toxicity
Publications
Fraisinib: a calixpyrrole derivative reducing A549 cell-derived NSCLC tumor in vivo acts as a ligand of the glycine-tRNA synthase, a new molecular target in oncology - Frontiers in Pharmacology (2024) Two calix[4]pyrroles as potential therapeutics for castration-resistant prostate cancer - Investigational New Drugs (2022) A novel calix[4]pyrrole derivative as a potential anticancer agent that forms genotoxic adducts with DNA – Scientific Reports (2018)



